Low testosterone

Can a pituitary problem cause low testosterone?

Yes. Low testosterone can start in the testes (primary) or in the pituitary or hypothalamus that signal them (secondary). LH and FSH tests help tell the two apart.

Secondary causes include pituitary conditions, some medicines, significant illness and obesity.

Finding the cause can change the next step, including whether further testing is recommended.

Risks and limitations

Some causes need specialist evaluation beyond hormone replacement.

Sources

Endocrine Society — Testosterone Therapy in Men With Hypogonadism guideline (2018)
Endocrine Society — Hypogonadism (low testosterone) patient resource

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