Healthy aging

What side effects can NAD+ injections cause?

Reported effects include injection-site discomfort and, for some people, flushing, nausea or a general feeling of discomfort around the time of the injection. Tell your clinician about anything you notice.

Formal human safety data for injected NAD+ is limited, which is part of why it is used with physician oversight.

Your clinician may adjust the plan if side effects are bothersome.

Risks and limitations

Because evidence is limited, unknown risks cannot be ruled out.

Sources

Grant R, et al. A pilot study investigating changes in the human plasma and urine NAD+ metabolome during a 6-hour intravenous infusion of NAD+. Front Aging Neurosci. 2019 (PubMed)
FDA — Compounding and the FDA: Questions and Answers

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